Short description of the units of the Department of Physiology

Experimental Neonatology Research Group

Principal investigator:Ferenc Domoki, MD, PhD

 

Researchers:

Viktória Kovács MS,PhD

Gábor Remzső MSc

Valéria Tóth-Szűki BSc

 

Our study field is the so-called hypoxic-ischemic encephalopathy (HIE) induced by perinatal asphyxia in term neonates. We focus both on revealing the pathophysiological mechanisms of neuronal-vascular damage leading to HIE and testing promising putative neuroprotective strategies.

To achieve our goals, we utilize a subacute HIE animal model,the newborn pig that is appropriate for clinical translation.

Our research methods involve continuous monitoring of the physiology and cerebral electrical activity of the animals, performing in vivo studies on the cerebrocortical microcirculation and neuronal activity, and analysis of the obtained brain samples using histological and molecular biology techniques.

 

 

Sleep research

Lab chief: Lelkes Zoltán, MD, PhD

 

 

 

Translational Behavioral Neuroscience Group

Development and characterization of a complex schizophrenia rat model.

Our laboratory developed a new, complex schizophrenia rat model. The goal of the recent studies to characterize the animals applying different behavioral tests.

1. Investigation of pain threshold of the "schizophrenic rats". 2. Investigation of cognitive functions of the "schizophrenic rats". 3. Investigation of autonomic functions of the "schizophrenic rats".

 

Lab chief:Gyöngyi Horváth, MD, PhD

 

Researchers:

Gabriella Kékesi MS, PhD

Alexandra Büki MS,PhD

Leatitia Adlan

 

 

 

Sensory research

Chemosensitive primary sensory neurons expressing members of the TRP receptor family (e.g. the capsaicin receptor) play a central role in the transmission of pain. In the Laboratory of Functional Neuromorphologyl we study the anatomical and functional properties of chemosensitive primary afferent neurons in animal models and neuronal cell cultures under physiological and pathophysiological conditions. We apply behavioural tests, laser Doppler flowmetry and light and electron microscopic functional neuromorphological techniques to examine pain mechanisms and, in particular, nociceptive functions.

 

Lab chief: Dux Mária MD, PhD

 

Researchers:

Jancsó Gábor, MD,PhD,DSc

Sántha Péter MD, PhD

Kisné Dobos Ildikó MS

Oszlács Orsolya MS

Tóthné Rosta Judit Mária MS, PhD

Karcsúné Kis Gyöngyi MS, PhD

 

PhD students:

Pálvölgyi Laura

Dr. Friedrich Nadine

 

 

Sensorimotor Research Group

Research topic:

Examination of parallel visual pathways in the mammalian brain.

Electrophysiological and anatomical investigation of multisensory and sensorimotor functions of the ascending tectofugal visual system and the connected basal ganglia in the mammalian brain.

Psychophysical and EEG investigation of visual associative learning in human. Sleep investigation on rats.

 

 

Lab chief: Attila Nagy MS, PhD

 

Lab co-chief: György Benedek MD, PhD, DSc

 

Researchers:

Balázs Bodosi MS, PhD

Szabolcs Kéri MD, PhD, DSc

Marietta Orosz-Ábel MS, PhD

Kálmán Tót MSc

Ádám Kiss MSc

 

Diploma students:

András Hegedűs

Márton Gaszner

Bátor Brassó

Bulcsú Szűcs

Viktória Rácz

Olívia Huszár

Noémi Pintér-Harcsa

Scientific partners:

Dr. Gábor Braunitzer

Gabriella Eördegh MS,PhD (ETSZK)

András Kelemen MS,PhD SZTE JGYPK

Péter Gombkötő MS, PhD (Center for Molecular and Behavioral Neuroscience, University Rutgers, USA)

 

 

Primate Vision research

Mammalian electrophysiology Extracellular single cell activity recording in the visual and frontal cortices to investigate visually based decision making Human psychophysiology The effects of transcranial DC stimuli on magnocellular-pathway related decisions The organization of the mental lexicon in bilingual individuals The effect of perceptual learning on multimodal processing The investigation of implicit sequence learning using psychophysics and elctrophysiology (EEG)

 

Lab chief: Sáry Gyula MD, PhD, DSc

 

Researchers:

Dr. Benyhe András

Dr. Fehér Ágnes, PhD

Péter Kaposvári, PhD

Szemenyeiné Mikite Katalin

Student research associates:

Eperjesi Dávid

 

 

 

 

Neural Network Research Group

We are investigating the emergent activity patterns of neuronal networks during healthy and pathologic conditions in freely moving animal models. Optogenetic and high-resolution electrophysiological techniques are combined to investigate the network mechanisms during the development of epileptic seizures. We are making attempts to develop a transcranial electrical stimulation approach that can automatically terminate seizures in their early stage through a closed-loop system. Another focus of our work is on the neuronal basis of memory processes and spatial navigation in the hippocampus and related structures. The official language of the lab is English, talented undergrad students with good background in informatics/math/biophysics/biology and good manual skills are welcome.

Lab chief: Berényi Antal, MD, PhD

 

 

Researchers:

Nagy Anett

Yuichi Takeuchi

Mari Takeuchi

Qun Li

Rodrigo Alejandro Sierra Ordonez

Ráfi Péter

 

Student research associates:

Lizeth Katherine Pedraza Correa

Pejin Andrea

Vecsernyés Endre

Barcsai Lívia

Földi Tamás

Langó István

Masahiro Ohsawa PostDoc

Harangozó Márk TDK student

 

 

Project manager:

Gyurkovics Tamás BSc

For more information please visit our website at www.berenyilab.com